Evaluating The Effect Of Remdesivir On The Mortality Rate And Recovery Of COVID-19 Patients In The Intensive Care Units Of Shohdaye Ashayer Hospital In Khorramabad In The First Half Of 2020

Abstract

Title: Evaluating the effect of remdesivir on the mortality rate and other outcomes of COVID-19 patients in
the intensive care units of Shohdaye Ashayer Hospital in Khorramabad in the first half of 2020
Introduction: Researchers are looking for safe and effective treatment methods Due following the emergence
of SARS-CoV-2. Remdesivir is currently being evaluated for clinical efficacy and safety in COVID-19
patients. The present study evaluates the effect of remdesivir on the mortality rate and other outcomes of covid-
19 patients in the ICUs of Shohdaye Ashayer Hospital in Khorramabad in the first half of 2020.
Methods: In this retrospective cross-sectional descriptive study, 35 patients’ medical records in each group
were reviewed. Patients were divided into two remdesivir and control groups. In this regard, 35 subjects in the
remdesivir group received remdesivir in addition to the standard diet, and 35 people in the control group
received only the standard diet. The two groups were compared regarding the frequency distribution of
underlying characteristics, the effect of the drug on the length of stay in the hospital and ICU, the effect of the
drug on mechanical ventilation, and the recovery and mortality rate.
Results: In the remdesivir group, 18 were male and 17 were female. In the control group, 22 were male and 13
were female. In both groups, cardiovascular diseases were identified as the most frequent underlying diseases.
There was a significant difference between the groups regarding weakness and lethargy and respiratory distress
(P<0.05). There was no significant difference between the two groups regarding the mean length of stay in the
hospital and ICU, the duration of recovery and mechanical ventilation, and the recovery and mortality rate of
the studied patients (P>0.05).
Conclusion: according to the results, remdesivir did not have any positive effect on the clinical outcomes of
the remdesivir group compared to the control group. The results of the present study did not consider the use
of this drug as an effective treatment in covid-19 patients.