Study the Effect of the Magnetic Field on the Healing of Bone Fracture after Implant Avian Bone in Femoral Bone in Rabbits

Abstract

Although the promotional effects on bone healing of static electromagnetic fields (PEMF) have been well demonstrated, the effects of static magnetic fields (SMF) remained unclear. In this study, effects of a custom-made magnetic wrap on radiographic and histopathological aspects of bone healing using a femoral rabbits unstable osteotomy gap and implant avian  model were investigated. After an osteotomy of the midshaft femorus and avian bone implantation, bone healing was evaluated over an 22-days-period in the control rabbits (n = 5) and rabbits exposed to SMF (300 gauss) (n = 5). Bone healing was evaluated by qualitative and quantitative evaluation of serial radiographs every 2 weeks. Histopathological study was also performed on osteotomized femor upon completion of the experimental period. Rabbits exposed to SMF had more advanced radiographic healing of osteotomy sites. Cellular morphology scores of the SMF group was significantly greater as compared with the control group (P<0.05). These results suggested that using the osteotomy gap model, SMF enhanced the radiographic and histopathological aspects of bone healing in rabbits. Rabbits at risk for delayed healing of fractures may benefit from treatment with SMF.