Anticancer Evaluation of Innovated Macrocyclic Sulfazan and Triazan Compounds as anticancer- Breast Drugs

Abstract

Triazan  with  Macro cyclic Sulfazan  as a novel  class of compounds were attended  and developed for the primary stage in organic chemistry in 2019 internationally by (Professor Dr. Nagham Aljamali), who began working on studying of these chemical compounds in the field of cancerous tumors and comparing infected cells with healthy cells by using many materials prepared from the interaction of chemical compounds that include donor atoms that can attack and treat malignant tumor cells, such as sulfur and nitrogen atoms, which are considered as a measure of the ability of drugs to treat Diseases through knowledge of the ability of triazan  and formazan compounds to penetrate cellular membranes, while there are special medicinal compounds that often lose this ability, and in this case it was found that antibiotics become highly effective and their activity increases in the presence of groups of Formazan, Triazan  and Sulfazan. Sulfazan  compounds differ in their mode of action and activity in the life system depending on their composition. For example, inert (stable) metal complexes have good effectiveness against microbes, fungi, and viruses. They are also used to control the spread of cancerous tissues.. All spectral studies appeared good results and strong evidences for  their structures and all results of anticancer studies indicated  to high efficiency of these compounds on cancer cells of breast.