An In Vitro Investigation of Antimicrobial Efficacy Of Murraya Koenigii Leaves (Curry Leaf Plant) And Its Bioactive Component Quercetin Against Selected Pathogenic Microorganisms

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Himani Badoni, Gaurav Giri, Ayushi Chaudhary, Promila Sharma, Apurva Kshatriya, Meenakshi Pant, Swati Sinha

Abstract

Murraya Koenigii, (family: Rutaceae) commonly known as curry leaf plant, is a green leafy plant found all over India. They have been long used for their medicinal properties. Owing to the presence of various bioactive compounds such as phytochemicals they can act on various microorganisms (including bacteria) inhibiting their growth or killing them as a whole. This study focuses on the demonstration of their antibacterial properties. For this, leaf samples from two different locations were taken to produce a comparative result. Four test bacteria were taken viz Pseudomonas aeruginosa, Bacillus subtilis, Klebsiella pneumoniae and Staphylococcus aureus. Methanolic extracts were prepared for the leaf samples and standard agar well diffusion method was chosen for the study. Furthermore, quercetin, a bioactive compound found in the leaves of M. koenigii, was tested to demonstrate its individual antibacterial activity. The present study showed the effective antibacterial activity of both leaf samples along with its bioactive component quercetin, and quercetin showed effective results inhibition against different bacterial strains.  Therefore, Quercetin can be used as a potent therapeutic in pharmaceutical industry.

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