Association of Protein Z with Diabetes Type 2 in Iraqi Patients that Previously Attacked with Covid 19.

Abstract

Diabetes mellitus comes in a variety of forms, insulin resistance and absolute or relative insulin insufficiency (T2DM). The ongoing pandemic of COVID-19 has significantly affected blood glucose level in patients with diabetes mellitus. PROZ, a member of the coagulation class, inhibits activated factor X directly at the phospholipid surface, to reduce blood coagulation. PROZ suggested that alterations in their levels may be associated to vascular problems. The study included subjects T2DM with COVID 19, T2DM without COVID 19, Control with COVID 19, and control without COVID 19, for cytokine analysis. Blood samples of the subjects were assessed for PROZ and other parameters. Authors were identified PROTZ that differed by 1-fold or more in at least one out of the three comparisons T2DM with COVID 19 VS. Control with COVID 19, and T2DM without COVID 19 VS. control without COVID 19. Serum PROZ levels were found to be increased in T2DM with COVID 19 and T2DM without COVID 19 compared to those in control (P<0.005). There were association between PROZ and hemoglobin HbA1c. PROZ might be an effective biomarker for spotting diabetes.