Effect of the efficacy of cabbage extract on the level of certain antioxidants in white male rats exposed to carbon tetrachloride

Abstract

The current study aims to find out the protective effect of the aqueous extract of the leaves of the cabbage plant in both green and red types in reducing oxidative stress induced by carbon tetrachloride and activating antioxidants in male white rats.

 50 Swiss male rats were used, and distributed into 10 equal groups and placed in plastic cages containing each cage of 5 rats that underwent appropriate laboratory conditions, and the groups were divided as follows:

         Group I: Olive oil dose was given by tube feeding in the amount of 0.3 ml per rat,

         Group II: CCl 4 was given in the amount of 0.2 ml after mixing it with equal amounts of olive oil by peritoneal injection, meaning (we take 1 ml of olive oil and mix it with 1 ml of CCl 4) and this becomes ready for peritoneal injection,

         Group III: CCC4 was injected by 2 0.ml by peritoneal injection for four weeks, after which the aqueous extract of green cabbage was given 1 ml,

         Group 4: CCl4 was injected in .2 0 ml by peritoneal injection for four weeks and then given the aqueous extract of red cabbage in the amount of 1 ml,

         Group V: CCl 4 was injected by 0.2 ml by peritoneal injection for four weeks, after which the aqueous extract of green and red cabbage was given 1 ml

         . Group F: Salmarin was given 1 mg per rat.

         Group G: Aqueous extract of green cabbage was given in the amount of 1 ml.

         Group H: Aqueous extract was given to red cabbage in the amount of 1 ml,

         Group IX: Aqueous extract was given to green and red cabbage in the amount of 1 ml,

         Group X: Control group was given 3 ml distilled water and by gastric feeding tube with the provision of the diet.

Then blood samples were drawn and serum was separated by common methods and catechin tests were conducted on it, and the results of the treated groups were as follows:

1)         The results showed a significant increase in the concentration of (MDA) Mallondialdehyde in the groups injected with carbon tetrachloride.

2)         The results showed a significant increase in the concentrations of Catalase (CaT), Glutathion Peroxidase , SOD) ) Superoxide Dismutse (GPx)   In carbon-free aggregates

3)         A significant decrease in the concentration of Mallondialdehyde was observed in the groups dosed with green and red cabbage and the group of salmarin herb (free of carbon tetrachloride).