Estimation the level of some enzymes (as Remarker) in serum of women with Breast Cancer (B.C) in Salah al-Dien Governorate

Abstract

The research encompassed a sample of 180 breast cancer patients and 50 control subjects. This investigation aimed to assess the activity of several notable enzymes present in the serum of women diagnosed with breast cancer, in order to determine their potential significance in breast cancer diagnosis. Enzymatic methods were utilized to measure the levels of Alkaline Phosphatase (ALP), 5-Nucleotidase (5'-NT), Acid Phosphatase (ACP), Aspartate Aminotransferase (AST), and Alanine Aminotransferase (ALT) activity. A considerable increase in the catalytic activities of ALP, 5-NT, ACP, AST, and ALT was observed (P < 0.001 for all) in the serum of breast cancer patients both pre- and post-chemotherapy compared to the control group.

In conclusion, this study strongly suggests that ALP, 5-NT, ACP, AST, and ALT may serve as significant biomarkers in the context of breast cancer diagnosis.