A comparison effects of autologous platelet-rich plasma gel and low-level laser therapies on induced cartilage defects: An experimental study

Abstract

Most surgeons have tried to use modern techniques to treat lots of surgical cases in veterinary medicine. This study aims to compare the effects of autologous platelet-rich plasma (PRP) and laser therapies on induce elastic cartilage defects in sheep. Twelve healthy sheep were divided into 3 groups, G1 was treated with autologous PRP gel with different platelet counts, G2 was treated with laser radiation with different doses and G3 was treated with normal saline and was used as control group.the left ear cartilages of all animals were incised at 5 cm, while at 6 mm diameter, a full thickness hole was inserted in the right ear. G-1 was treated with platelet-rich plasma gel, 3 ml daily for one week. Two of G2 was treated with 820 nm laser and the other two were treated with 860 nm laser daily for one week. In addition, G-3 were treated with normal saline daily for one week.Biopsies were taken at 1, 6 weeks for histo-pathological examination to compare the healing performance of each type of treatment. Histopathological evaluation showed the beneficial therapeutic effect of autologous PRP compared to laser therapy and the PRP therapy has more beneficial effect than laser therapy, its preparation is very simple and cheaper than laser which requires expensive equipment and dangerous side effect when used.