Assessment Of Antibacterial Activity and Antioxidant Screening of Hemidesmus Indicus Root Extracts

Abstract

The Hemidesmus indicus is used to cure leprosy, leucoderma, itching, skin disease, asthma, bronchitis, leucorrhoea, dysentery, piles, syphilis, and paralysis. The present study was aimed to investigate the antioxidant and antibacterial activity of Hemidesmus indicus root. The root extracts of Hemidesmus indicus were prepared using different solvents like Methanol, Ethanol, Chloroform, Petroleum Ether and Aqueous. The antibacterial activity of different extracts of Hemidesmus indicus root was tested by disc diffusion method. Zones of Inhibition produced by different extracts in a dose of 100 and 200 mg/ml against selected strains was measured and compared with those of standard drug Streptomycin. The highest zones of growth inhibition were exhibited by ethanol extract against all the microorganisms compared to other extracts. The antioxidant activity of the root extracts was performed. On the basis of the results, it can be concluded that the petroleum ether extract of Hemidesmus indicus root possess significant antioxidant activity against in vitro studies.