Comparative GC-MS Analysis Of Gomutra Sadhita Triphala Kwatha And Gomutra Sadhita Triphala Arka

Abstract

Ayurveda is the science of life, which is dealing with life for 5000 years without any change in basic principles.Panchavidha Kashaya Kalpana are primary preparations that are considered underneath fundamental principles of Bhaishajya Kalpana. They are Swarasa, Kalka, Kwatha, Hima and Phanta and are recommended to consume immediately (sadyosevana). Kwatha Kalpana being one of them has low shelf life, hence same Kalpana can be converted into Arka Kalpana to increase its shelf life up to a year. Arka Prakasha, the classical Ayurveda book mentions the distillation techniques for separation of the volatile bioactive compounds from a drug by using Arka Yantra. In the present study Gomutra sadhita triphala kwatha formulation mentioned in Shotharogadhikara in Bhaishajya Ratnavali textbook is
modified into Arka Kalpana taking media as Gomutra. Furthermore, traditional Gomutra sadhita triphala kwatha (GTK) and Gomutra sadhita triphala Arka (GTA) both were subjected to GC-MS analysis.
Method: The present study mainly focuses on GC-MS evaluation of Gomutra sadhita triphala kwatha and Gomutra sadhita triphala Arka for detection of different components present in them. The comparative analysis will define the efficacy of respective dosage form. The preparation of both the forms of medicines was conducted at GMP certified Parul Ayurveda Pharmacy, Parul university.
Conclusion: Present study reveals that both dosage forms GTK and GTA contains entirely different components. Arka contains more volatile compounds having Anti-inflammatory effect. on contrary the Kwatha has the components which can exert protein denaturation and thereby act as anti-inflammatory.