To Design And Develop Cetylpyridium Chloride Combination With Azadirachta Indica Extract Antibacterial And Antimicrobial Effervescent Mouthwash

Abstract

Present work lead to the optimization of process for preparation of lyophilize Mouthwas solution and development of effervescent tablet comprising a solid water soluble excipient i.e. glycine, sorbitol, aspartame which dissolve in 160 seconds. Formulation being a solid dosage form, the predicted stability of Cetylpyridium Chloride and Azadirachta Indica is more, as Mouthwas solution is available in liquid form and possesses stability problems if not stored at low temperature. Further a fast dissolving tablet strip will always be preferred by an end user over a liquid mouthwash bottle. The said formulation will be widely useful for a traveler, tourist or a camper, as it is difficult to carry liquid mouthwash bottle with him because of weight, fragility or bulk hence offering patient compliance and also solving the problem of shelf space at the retail outlet and home.