In-Vitro Study Of Formulation And Development Of A Transdermal Patches For Anti-Inflammation And Its Evaluation

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Sachin Dimri
Pallavi Sati
Mansi Nautiyal
Vijay Laxmi Trivedi
Priyanka Bankoti
Jayanti Ballabh
Sunil Prakash
Gaurav Jain
Neha Saini

Abstract

Conventional drug delivery system has many problems so bulk of research has now shifted from synthetic drugs to herbal drugs. This is possible because of the vast variety of bioactive molecules in the plants and their higher safety margin. This present study is focused on the use of Adhatoda vasica flower and Ricinus Communis leaves as an antioxidant agent. The main objective of present work was to develop the transdermal patch so that minimize the side effects and maximize the therapeutic efficacy. The formulations were also examined for organoleptic properties as well as other physicochemical features as thickness, weight homogeneity, folding durability, moisture content, and medication content.

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Author Biographies

Sachin Dimri

Sai College of Pharmacy, Dehradun-248001, Uttarakhand, India.

Pallavi Sati

High Altitude Plant Physiology Research Centre, Hemvati Nandan Bahuguna Garhwal University (Central University), Srinagar-246174, Uttarakhand, India.

Mansi Nautiyal

Department of Agriculture, Tula’s Institute, Dehradun-248197, Uttarakhand, India.

Vijay Laxmi Trivedi

High Altitude Plant Physiology Research Centre, Hemvati Nandan Bahuguna Garhwal University (Central University), Srinagar-246174, Uttarakhand, India.

Priyanka Bankoti

School of Agricultural Sciences, Shri Guru Ram Rai University, Dehradun, 248001, Uttarakhand, India. 

Jayanti Ballabh

School of Agriculture, Uttaranchal University, Dehradun 248007, Uttarakhand, India.

Sunil Prakash

School of Agriculture, Uttaranchal University, Dehradun 248007, Uttarakhand; India

Gaurav Jain

School of Agriculture, Uttaranchal University, Dehradun 248007, Uttarakhand, India

Neha Saini

School of Agriculture, Uttaranchal University, Dehradun 248007, Uttarakhand, India.