The management of Vulvovaginal Candidiasis (Kaba Yoni) by Siddha herbo-mineral formulation Linga Chenduram through In-Vitro study

Abstract

Background: Candidiasis are common oral and genital infection in humans and nowadays candida species have shown resistance against various synthetic medicines. Linga Chenduram is mentioned in Siddha classical literature and indicated for Mega Noi (Sexually Transmitted Disease).  Linga Chenduram was subjected to assess antifungal activity.

Methods: The antifungal activity of the sample was tested for Candida albicans ATCC 10231 to Determine the diameter of inhibition zone (DIZ) by disc diffusion and broth microdilution methods, Minimum inhibitory concentration (MIC), and Minimum fungicidal activities (MFC).

Result: The study results revealed that the DIZ for 100µg of Clotrimazole, 500μg, and 1000μg of sample drug is found to be 29mm, 14mm, and 17mm respectively. MIC 50 Value of Linga Chenduram is 281.086µg/ml.

Conclusions: So it can be concluded that Linga Chenduram possesses effective antifungal activity against Candida albicans.