Investigation Of Antidepressant Activity Of Nardostachys Jatamansi

Abstract

Nardistachys Jatamansi belongs to the family Valerianaceae have pharmacological actions like hepatoprotective, cardioprotective, hypolipidemic, antidiabetic, antioxidant, antifungal.

Anxiety and Depression are widespread psychiatric disorders affecting around 5% of the population. Furthermore, it is difficult to predict which patient will respond to any given treatment. In the traditional systems of medicine, many plants have been used to treat anxiety and depression for thousands of years. The present study was designed to evaluate the antidepressant activity of the alcoholic and aqueous extracts of Nardistachys Jatamansi rhizomes in rodents. The antidepressant activity was tested by using forced swim test and tail suspension test. The results infer that reduced immobility time elicits antidepressant activity. It was concluded that alcoholic and aqueous extracts of Nardistachys Jatamansi rhizomes having antianxiety and antidepressant activity. Alcoholic extract of Nardistachys Jatamansi rhizomes showing more significant activity over the aqueous extract.