QSAR Study on Photoinduced Toxicity of Polycyclic Aromatic Hydrocarbons

Abstract

The paper describes Quantitative Structure Activity Relationship (QSAR) study for photoinduced toxicity of polycyclic aromatic hydrocarbons (PAHs). These compounds are extremely toxic in the presence of sunlight. Connectivity type topological indices yielded excellent models. Higher parametric models were found to be statistically more significant. The results are critically discussed on the basis of variety of statistical parameters.