Comparative In-Vitro Parasiticidal Properties Of Euphorbia Milii And Euphorbia Microphylla Linn Root Extracts

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S. R. Kane
S. K. Mohite
S. V. Jawarkar
S.M. Kanoje
S.R. Fulmali
A. M. Kandalkar

Abstract

Methanol infusions of the leaves and stems of Euphorbia microphylla Linn and Euphorbia milii were investigated for
antifungal activity against Fasciola gigantica, Taenia solium, and Pheritima pasthuma, respectively. The bioassay
consisted of determining the time between worm paralysis and death at five dosages (10-100mg/ml) of each extract. All of the extracts demonstrated strong antibacterial action, with P. pasthuma being the most sensitive to the worms followed by F. gigantica and T. solium. The most active extracts were E milii and E microphylla Linn roots extracted with methanol. The test used piper zine citrate (10mg/ml) and distillation water as the recognized reference medication and management, respectively.

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Author Biographies

S. R. Kane

Research Scholar, Department of Pharmaceutical chemistry, Rajarambapu College of Pharmacy, Kasegaon.
Shivaji University Kolhapur, India.

S. K. Mohite

Research Scholar, Department of Pharmaceutical chemistry, Rajarambapu College of Pharmacy, Kasegaon.
Shivaji University Kolhapur, India.

S. V. Jawarkar

S. D. Patil Institute of Pharmacy, Islampur Sangli, India

S.M. Kanoje

L.S.R.G., Institute of Pharmacy, Akola, India

S.R. Fulmali

S.G.S.P.S. Institute of Pharmacy, Akola, India

A. M. Kandalkar

Vidyaniketan College of Pharmacy, India