Antidiabetic Activity Tinospora Cordifolia Root On Streptozotocin Induced Rats

Abstract

Diabetes is a chronic disorder. It may be characterized by hyperglycaemia. These may help in insulin secretion defects
and both insulin action. Due to development of insulin resistance the inadequate insulin secretion and tissues dimension
may lead to abnormalities of fats, carbohydrate and metabolism of protein. Now a days, some herbal formulation is been
used for this treatment like pedes of ginseng: it was used for health promoting. Present study shows evaluation of
antidiabetic activity on root of T. cordifolia on experimental animals. Type 1 and type 2 diabetes is been introduced into
Wistar Albino rats by STZ (Streptozotocin) and it was treated with the ethanolic root extract of T. cordifolia by using
different concentration (150, 250 and 300 mg/kg/day). Extracts of T. cordifolia root extract shows the great efficacy in
anti-diabetic activity in normal and Wistar albino diabetic rats.