Molecular Detection Of Rifampicin Resistance Among Mycobacterium Tuberculosis (MTB) Patients In Iraq

Abstract

It was found that the rate of resistance to the standard drug Rifampicin for patients with Mycobacterium tuberculosis (MTB) and non-recovery in most Iraqi governorates was 13%, while the rate of sensitivity to the standard drug Rifampicin was 87% according to the DST test, while the rate of resistance to Rifampicin was 68.4% and the sensitivity was 31.6% according to (L.P.A) test for the same samples under study, and it is clear that the most infected regions of Iraq with Mycobacterium tuberculosis (MTB) were in the city of Baghdad and the least in the province is Anbar, and the most response ages to the standard drug Rifampicin were the ages confined between 10 years to the age of 50 years and the highest rate of response Between 40-50 years, the response rate deteriorated after the age of 70 until the age of 80.

It turned out that the incidence of Mycobacterium tuberculosis (MTB) for males was higher than for females. There was a clear significant difference between the infections of Mycobacterium tuberculosis (MTB) between the people who live in urban areas and between people who they live in rural areas.

It was also found that the Resistance type for (MDR), (RR) and (MONO) were 47.1%, 23.5% and 17.6%, respectively. This indicates that the best antibiotic that may be used in the treatment of Mycobacterium tuberculosis (MTB) is Rifampicin.