Pharmacognostic Evaluation, Phytochemical Screening And Isolation Of Bioactive Compounds Of Different Plant Extracts On Diarrheal Activity

Abstract

In recent times, there has been a growing interest in exploring the therapeutic and medical potential of natural plant-derived extracts. This study aimed to investigate the impact of different solvents, including methanol, n-hexane, chloroform, ethyl acetate, and water, on the phenolic profile and their associated antioxidant and antidiarrheal properties. As a benchmark antioxidant, ascorbic acid was used to assess the radical-scavenging abilities of leaf extracts from commonly used medicinal herbs. The study employed the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical to evaluate the scavenging activity. Phenolic compounds are known for their bioactive properties, especially their antioxidant effects. Notably, the leaves of R. ellipticus, Woodfordia fruticosa, and Quercus leucotrichophora exhibited the highest overall antioxidant activity. The primary objectives of this study were to determine phenolic content, reduction power in various leaf extracts, and assess their antioxidant properties using the DPPH and ABTS assays