Association of Hepatitis B Virus Infection and Risk of Pancreatic Cancer: A Review

Abstract

According to an estimate,  approximately, 350 million people  frequently suffer with the hepatitis B virus (HBV), which can be spread by sexual promiscuity, working in the medical sector, undergoing dialysis, receiving transfusions of unscreened blood, getting tattoos, having a close relationship with an HBV carrier, and reusing injections by intravenous drug users. A chronic HBV infection can develop into pancreatic cancer due to the key risk factor for pancreatic cancer in patients suffering from hepatitis B, which is primarily genetic. Genetic variables take precedence over other criteria, such as the patient's blood type. Additionally, factors including smoking, being overweight, drinking alcohol, and H. pylori infection all have a significant effect. However, even if none of these factors apply to a patient, their risk of developing pancreatic cancer is still quite high if their family has a history of the disease. This review suggested that pancreatic cancer was given a new diagnosis in 196,000 people globally in 1990. 441,000 cases were discovered in 2017 across the globe. Pancreatic cancer is ranked 11th among the most frequently occurring cancer causing mortalities throughout the globe. Pancreatic cancer had 45,918 new cases of diagnosis in 2018, and it claimed 432,242 lives worldwide. In America in 2019, there were more than 45,000 deaths from pancreatic cancer and 56,000 new cases. The death rate associated with this illness is predicted to have doubled in both Europe and America by 2030