The Role Of Biologic Therapies In Improving Joint Health In Autoimmune Arthritis

Authors

  • Shayim Saud Alanazi
  • Ibrahim Hassan Almalki
  • Abdulaziz Amin Alandijani
  • Hassan Mohammed Thubab
  • Haifa Saud Alkheledan
  • Shahad Ali Alsufyani
  • Salma Awadh Alharthi
  • Abdullah Mansoor Al nass
  • Ibrahim Ali AlSultan
  • Ali Mohammed Alshahrani
  • Abdullah Fuad Aborukbah

DOI:

https://doi.org/10.53555/sfs.v10i5.2298

Keywords:

Ankylosing Spondylitis, Biologic Therapies, Rheumatoid Arthritis, Psoriatic Arthritis, Joint Health

Abstract

The field of autoimmune arthritis treatment has seen changes due to the introduction of therapies transforming how conditions like rheumatoid arthritis (RA), psoriatic arthritis (PsA), and ankylosing spondylitis (AS) are managed. For RA, starting treatments like tumor necrosis factor alpha (TNF α) inhibitors, interleukin 6 (IL 6) receptor antagonists, and Janus kinase (JAK) inhibitors are crucial for achieving remission and preventing joint damage. JAK inhibitors like tofacitinib offer options with administration. Managing Psoriatic arthritis involves using TNF α inhibitors as therapies, while IL-17A inhibitors address joint and skin issues comprehensively. Tailoring treatment plans based on characteristics leads to better results in this complex condition. Ankylosing spondylitis poses challenges where TNF α inhibitors and IL 17A inhibitors vital in reducing disease activity and enhancing spinal mobility. Incorporating physical therapy highlights the approach needed for outcomes in ankylosing spondylitis. The conversation explores the intricacies of using therapies, highlighting how clinical management continues to evolve. Regular monitoring, involving patients in decision-making, and having an understanding of backgrounds are key elements for navigating the ups and downs linked with biological treatments. To sum up, the analysis highlights how biological treatments have significantly changed the way autoimmune arthritis is handled. Tailored approaches that take into account the nature of the disease and individual patient choices play a role in enhancing joint health and overall quality of life.

 

Author Biographies

  • Shayim Saud Alanazi

    Department of Orthopaedic, King Khalid Hospital, Tabuk, Saudi Arabia

  • Ibrahim Hassan Almalki

    Ain Shams Primary Healthcare Center, Mecca Health Cluster, Mecca, Saudi Arabia

  • Abdulaziz Amin Alandijani

    Department of Pediatric Emergency, Al Aziziya Children Hospital, Jeddah, Saudi Arabia

  • Hassan Mohammed Thubab

    Occupational Health Department, King Fahad Central Hospital, Jazan, Saudi Arabia

  • Haifa Saud Alkheledan

    Public Health, Riyadh First Health Cluster, Riyadh, Saudi Arabia

  • Shahad Ali Alsufyani

    Wast Almadinah Primary Healthcare Center, Ministry of Health, Taif, Saudi Arabia

  • Salma Awadh Alharthi

    Department of Internal Medicine, King Abdulaziz Specialist Hospital, Taif, Saudi Arabia

  • Abdullah Mansoor Al nass

    Department of Family Medicine, Qatif Health Network, Qatif, Saudi Arabia

  • Ibrahim Ali AlSultan

    Department of Family Medicine, Qatif Health Network, Qatif, Saudi Arabia

  • Ali Mohammed Alshahrani

    Department of Nephrology, King Abdulaziz Hospital, Jeddah, Saudi Arabia

  • Abdullah Fuad Aborukbah

    Department of Orthopedics, Al Thager Hospital, Jeddah, Saudi Arabia

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Published

2023-11-12