To Study The Phytochemical Screening And Antioxidant Activity Of Cassia Fistula And Boerhaavia Diffusa Leaf Extracts On Hepatotoxicity

Abstract

Hepatotoxicity is the medical term used to describe liver damage caused by toxins, dietary or herbal supplements, or pharmaceuticals. The most common reason for a pharmaceutical being withdrawn from the market after it has been approved is due to an adverse drug reaction. Hepatotoxicity can manifest as either acute or chronic, and its symptoms, which resemble those of various other hepatobiliary diseases, can pose a challenge in terms of identification. This study aimed to investigate the antioxidant activity and phytochemical properties of the leaves of the Boerhaavia diffusa and Cassia fistula plants. Phytochemical and antioxidant tests were conducted on leaves. Ascorbic acid was utilized as a reference antioxidant to assess the ability of leaf extracts from regularly used medicinal herbs to scavenge radicals. The experiment utilized the DPPH free radical to evaluate the scavenging activity. The antioxidant actions of phenolic compounds, including their bioactive characteristics, are widely recognized and accepted. Notably, the leaves of Boerhaavia diffusa and Cassia fistula had the highest overall antioxidant activity. The primary objectives of this work were to assess the antioxidant capacities of various leaf extracts using the DPPH and ABTS assays, and to determine their phenolic content and reduction power