Investigation On The Pharmacological Properties Of Hibiscus Radiatus Leaf Extracts For Anti-Ulcer Activities

Abstract

The shrub Hibiscus radiatus is a member of the Malvaceae family. Known by another name, monarch rose mallow, it's a crop that grows easily in multi-cropping systems and is useful for both food and fibre, making it a perfect crop for impoverished nations. All of the plant's components are chopped, boiled, and used to make liquid concoctions since it is thought to be a blood purifier and fever cure5. Alkaloids, glycosides, phenolic compounds, tannins, sterols, steroids, saponins, flavones, flavonoids, proteins, amino acids, and carbohydrates are among the chemical elements that may be in charge of the biological functions.

For acute toxicity investigations, CPCSEA guideline No. 425 was adopted by the OECD. Two models were used to study the antiulcer activity of several Hibiscus radiatus extracts: the pyloric ligation method and the ethanol-induced ulcer model using rats. Omeprazole was used as the standard medication. Significant action has been demonstrated by methanol and aqueous extracts; among these, the aqueous extract of Hibiscus radiatus has demonstrated a highly significant antiulcer activity. According to the current study, Hibiscus radiatus leaf extracts have demonstrated strong antiulcer properties.