Possible Solutions to the Associated Cytotoxicity of Silver Nanoparticles

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Maha Mumtaz
Saliha Khalid
Attiqa Naz
Shumaila Shahzadi
Sidra Ahmad
Aiman Khan
Mamdudur Rahman
Amina Arif
Abbas Shahid

Abstract

Nanotechnology is the emerging field because of its antimicrobial and antibacterial activities. Because of these activities they can be used in different industries now-a-days. Because of this reason silver nanoparticles can be used in the drugs which may treat many fungal, bacterial and microbial diseases in human beings. Besides of these application, its concern related to the biological impacts of silver nanoparticles are also studied. Also their emerging risks and their problems in environment and living organisms are also studied. Many studies have been published in which their cytotoxicity effects on human health and on environment are investigated. An important factor related to the cytotoxicity of nanoparticles is that they may also increase the damage of genetic material as they can cross the cell membrane and nucleus because of their small size. So, there is an interest in studying the cytotoxicity of silver nanoparticles and also gives its possible solution to reduce its toxicity which may harm the human body or environment. For this reason, difference sizes of nanoparticles were used and synthesized to check their effect on environment and human body. Many studies are required for the solutions of the toxicity related to silver nanoparticles. This review is related to the recent works and publications and researches on the solutions of the toxicity related to silver nanoparticles and also about the more and safe application of silver nanoparticles. This study tells us that the silver nanoparticles which are naturally occurring are not toxic to the human body and environment instead of the silver nanoparticles which are artificially synthesized. This review also tells that that the human cells shows resistivity towards the cytotoxicity of silver nanoparticles while the silver nanoparticles toxicity may affect other organs very much. Also it concludes that how we can resist the toxicity of the chemically synthesized silver nanoparticles.

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Author Biographies

Maha Mumtaz

Department of Biochemistry, Faculty of Science & Technology, University of Central Punjab, Lahore 54000, Pakistan.

Saliha Khalid

Department of Material Science and Nanotechnology, School of Engineering and Natural Sciences, Kadir Has University, Cibali Campus Fatih 34083, Istanbul Turkey.

Attiqa Naz

Department of Pharmacy, Abasyn University, Peshawar.

Shumaila Shahzadi

Department of Anatomy and Histology, University of Veterinary & Animal Sciences.

Sidra Ahmad

Institute of Biotechnology and Genetic Engineering, The University of Agriculture Peshawar, Pakistan

Aiman Khan

Department of Dental Materials, Khyber Medical University Peshawar.

Mamdudur Rahman

Mechanical Engineering, University of South Carolina.

Amina Arif

Department of Biochemistry, Faculty of Science & Technology, University of Central Punjab, Lahore 54000, Pakistan.

Abbas Shahid

Department of Biochemistry, Faculty of Science & Technology, University of Central Punjab, Lahore 54000, Pakistan.