Modification in Electrophoresis Instrument and Analysis of Its Efficacy

Abstract

Electrophoresis is a key technique in biochemistry and molecular biology used to separate macromolecules by size and charge. This study aims to improve an electrophoresis instrument by modifying its design to boost functionality and efficiency. The key change involved reducing the size of the gel slab, which led to cost savings and improved separation resolution and reliability.

We evaluated the performance of the upgraded electrophoresis instrument by comparing it with a standard model using various DNA and protein samples. The results showed significant improvements in resolution, with clearer banding patterns and shorter run times. Statistical analysis confirmed that the enhanced instrument consistently delivered reliable and reproducible results across multiple trials.

Additionally, the modified instrument proved more versatile, accommodating a broader range of sample sizes and types. This enhancement extends its usefulness in both research and clinical diagnostics. Future work will focus on further optimizing the system’s parameters and conducting validation studies with a variety of sample matrices to fully realize the potential of the upgraded electrophoresis instrument.