Prevalence Of Mentally Retarded Syndrome and It’s Genetically Variation Among the Children of District Vehari Punjab Pakistan

Abstract

The aim of this study was to rule out to found the prevalence of mentally retarded syndrome and it’s genetically variation in children from Vehari district (Punjab, Pakistan). Mental retardation is a common intellectual execution that begin during the growth time of the child and associated with injury in adaptive behavior. Mental retardation is an assorted disease due to deformity and reduced functioning of brain.  The study was focused on the mentally retarded children and different genetic character of mentally retarded children and its prevalence was noted by observing different characters from the studied region. A questionnaire was developed to conduct the study and in that these studied characters were monitored by observing their height, earlobe structure, heart rate, palm structure, shortness in finger, hair line, facial dimple, PTC (Phenylthiocarbamide) test, color blindness, hair direction, cleft chin, tongue roll, and thumb direction. The findings indicate that 43% were color blind among the mentally retarded children and 61% showed high rate of heart beat, and 39% were with low heartbeat. 37.5% samples were Rh positive with A+ve and AB+ve blood group. Alleles of PTC genes were found positive in 82% of the total male samples while 17% of total female samples. Significant correlation was found among the different studied characters. This study will be helpful to know the prevalence of mentally retardation syndrome in the studied region with its proper identification by using the clinical symptoms.