Imaging studies with pathologic correlations showing the numerous different manifestations of pulmonary aspergillosis

Abstract

Depending on the patient's underlying immunological status, the burden of the organisms, and the underlying condition of the lungs, a pulmonary aspergillus infection might present itself in a number of different ways. Discussion: Patients who have a hyperimmune condition are often the ones that are diagnosed with hypersensitivity pneumonitis and allergic bronchopulmonary aspergillosis (ABPA) (asthma, atopy and hyper-eosinophilia). Patients who already have lung damage and cavities, most frequently as a result of a previous case of tuberculosis or sarcoidosis, are more likely to develop aspergilloma or mycetoma. In immunocompromised people, an infection with Aspergillus can manifest as either a semi-invasive or an invasive form of aspergillosis (angioinvasive and airway invasive, respectively). In this article, we correlate the radiologic findings of the various pulmonary manifestations of Aspergillus infection with their pathologic aspects to get a deeper comprehension of the disease process and a better understanding of the imaging patterns that are associated with it.