Effectiveness of I - PRF in Periodontal Regeneration - A Systematic Review And Metanalysis

Abstract

Objective: The purpose is to systematically review the current literature as to whether I-PRF is effective in regeneration of periodontal procedures, in adults in comparison to a control of traditional treatment.
Methods: A systematic electronic search of Medline, Scopus, Web of Science, and Embase databases was performed from 2019 to December 2022 using a combination of keywords. All in vitro and in vivo studies, written in English and concerning the potential role of I-PRF in regenerative dentistry were considered.
Results: Probing pocket depth and Clinical attachment level was decreased in subjects treated with injectable platelet rich fibrin as compare to the control group. Periodontal Index though was decreased in the study group, was not significantly different. Overall, it can be inferred that I – PRF was better in periodontal regeneration amongst the studies analysed in combination with surgical procedures
Conclusion: Current literature approves that i-PRF has shown to be a modern technology that produces dependable results in the field of dentistry. To ascertain the cell differentiation activity of i-PRF component, more investigation should be needed.