Prolonged Impact OfVitamin-D Deficiency And 1, 25-(OH)2 D3 (Vitamin-D3 Supplement) Of An Essential Endocrine Gland And Their Associated Hormones On Male Mice Mus Musculus(P).

Abstract

Many people nowadays, avoid getting enough sunlight, which directly leads to less production of vitamin-D, resulting in a weak immune system and a variety of disorders. Our primary goal is to investigate the impact on the Endocrine gland which is caused by Vitamin- D (Sunshine Hormone) deficiency in male adults, particularly the declining level of the Reproductive Hormone and its various metabolic disorders. Vitamin-D deficiency is now a days becoming a worldwide issue. Glands are very important in organism which contains various secretions and properly performs the all the metabolic functions of the body. Sometimes due to insufficient intake of diet (food intake) and many others, this leads to the decline in the level of nutrients such as Carbohydrates, Proteins, fats and Vitamins. Out of these, we are here mainly concern with vitamin which is a fat soluble vitamin (FSV) i.e. Vitamin-D commonly called as sunshine vitamin. Vitamin-D plays very pivot role in the metabolism of the organism, we use the male mice for our experimental work for the duration of the 90 days. We use the various methods to check the deficiency symptom which was caused by the Sunshine Vitamin-D. Reproductive Hormones was estimated statistically and histo-morphologically. We got statistical significant results in terms of certain parameters such as body weight while the prolonged effect of Vit.-D deficiency, reproductive fitness of the organism’s body through its important endocrine glands such as (lowering conc. of PTH and Testosterone level). We came to conclusion that due to the prolonged deficiency of Vitamin- D (Cholecalciferol) deficiency weight will be increased and also the level of the testosterone was also decreased which leads to the sexual disorders in males, which is now a day’s becomes a major global problem issues among the males and also hampers the reproductive fitness.