Review On Sustained Release Dosage Form: A Novel Approach And Its Evaluation

Abstract

Sustained release dosage forms are made to release a medication at a predefined rate while minimizing side effects and keeping a steady drug level for a certain amount of time. The fundamental idea behind a sustained release drug delivery system is to increase a medicine's usefulness while minimizing its negative effects and achieving illness cure by optimizing its biopharmaceutical, pharmacokinetic, and pharmacodynamic qualities. Sustained release drug delivery has a number of benefits over traditional dosage forms, including increased patient compliance because it requires fewer doses to be administered, decreased fluctuations in steady-state drug levels, maximum drug utilization, increased safety margin of potent drugs, shorter treatment periods and improved therapy that lower healthcare costs. Water penetration, polymer swelling, drug dissolution, drug diffusion, and matrix erosion have all been used as formulation techniques to measure drug release through matrix systems. This article provides a concise overview of different formulation strategies for drug delivery systems with sustained release.