Clinical application Protease from Acinetobacteria Species.

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Published: Dec 30, 2023
DOI: https://doi.org/10.53555/sfs.v10i3.3238
Keywords:
Protease, Acinetobacteria species and anti-inflammatory and anti- cancerous activity.

Main Article Content

Salunke.S M
Dr. Jadhav B. N
Dr. Satpute. R. A.

Abstract

Extracellular protease from Acinetobacteria species isolated from fish gut. The protease was produced and purified by ammonium persulphate, dialysis, Sephadex G column chromatography and Ion Exchange Chromatography and HPLC. Characterization was done by using BAPNA substrate and MALDI-TOF. Purified protease was studied for anti- inflammatory and anti-cancerous activity. The 50 percent inhibitory concentration was as followed for IL-6 0.348 mg/ml and LNCAP cell line 30.11µg/ml.

Article Details

Issue
Vol. 10 No. 3 (2023)
Section
Articles
Author Biographies

Salunke.S M

Department of Biotechnology, Vinayakrao Patil Mahavidyalaya, Art’s Commerce and Science College Vaijapur. Chhatrapati Sambhajinagar-423701, Maharashtra, India.

Dr. Jadhav B. N

Department of Zoology, Vinayakrao Patil Mahavidyalaya, Art’s Commerce and Science College Vaijapur. Chhatrapati Sambhajinagar-423701, Maharashtra, India.

Dr. Satpute. R. A.

Government Institute of Science, Department of Botany Chhatrapati Sambhajinagar-423701, Maharashtra, India.