Evaluation Of Whole Plant of Cardiospermum Halicacabum Linn for Anthelmintic Activity

Abstract

 Medicinal plants have been used in healthcare since time immemorial. About 80% of those who live in rural areas rely on herbal medicine as their primary form of healthcare. Cardiospermum halicacabum Linn is a member of the Sapindaceae family. An herbaceous climber, it is known as Mudakkathan in Tamil. It can be an annual or perennial. This plant's seeds, roots, leaves, stem, and stem are all used to treat a variety of illnesses and ailments. Cardiospermum halicacabum Linn's entire plant is being examined for anthelmintic action as part of this study, and its ethanolic, hydroalcoholic, and aqueous extracts have all undergone preliminary phytochemical examination. Whole plant extract was prepared using alcohol, hydroalcohol (50:50) and water. Anthelmintic property of whole plant of Cardiospermum halicacabum Linn. ethanolic, hydroalcoholic and aqueous extract was examined at 10mg/ml, 20mg/ml, 30mg/ml, 40mg/ml and 50mg/ml concentrations. The standard concentration utilised was piperazine citrate. Cardiospermum halicacabum Linn's anthelmintic action was demonstrated by the worms' paralysis and death at 5 hours, which was followed by a loss of motility and the fading of their body colours. Ethanolic extract was found to be potential anthelmintic drug. The preliminary study revealed the presence of various components that is alkaloids, flavonoids, tannins, sterols and triterpenoids, proteins and amino acids, carbohydrates.  Both aqueous and hydroalcoholic extract were found to be less significant. Thus, we can conclude that ethanolic extract of whole plant is a better crude drug of choice for anthelmintic activity.