Antimicrobial activity of essential oil (cajeput) against Streptococcus mutans

Abstract

Introduction The most familiar pathogen of the oral cavity is Streptococcus mutans which causes dental caries, the most common noncommunicable disease worldwide, leading to extraction and other secondary infections. In order to treat this condition, we need new formulations that are both effective and do not cause toxicity. Thus, the aim of this study is to check for the antimicrobial activity of cajeput, an essential oil against Streptococcus mutans.

Materials and methods Cajeput was obtained from XXXX industry, New Delhi. Streptococcus mutans was inoculated at 37°C and seeded on MHA medium. Agar well diffusion assay was used to measure antibacterial activity. Zone of inhibition was measured using a vernier caliper. Minimum Inhibitory Concentration (MIC) was determined by microbroth dilution method.

Results The well with the concentration of 40μl showed a maximum zone of inhibition of 5mm and the MIC value was 2.5mg/mL.

Conclusion From this study, it is observed that cajeput has antimicrobial activity against Streptococcus mutans and more studies should be conducted in order to learn its other properties such as antioxidant and anti inflammatory activity.