Evaluation of Antimicrobial activity and physical properties of Cinnamon modified Glass ionomer cement.

Abstract

Aim: The aim of the study is to evaluate antimicrobial activity and physical properties of cinnamon modified GIC.

Background: Dental caries can be defined as a biofilm-mediated, sugar-driven, multifactorial, dynamic disease that results in phasic demineralization and remineralization of dental hard tissues. GIC is the most used type of restoration in the primary dentition. Cinnamon extract has potent antimicrobial activity against numerous pathogenic microbes like E. coli, C. jejuni, S. enteritidis, and S. aureus that can be effectively capable of suppressing the growth of bacterial development. Hence the research on cinnamon modified GIC was done in this present study.

Materials and methods: The cinnamon extract was prepared. The powder and liquid of conventional GIC was mixed followed by the addition of the prepared extract with three different concentrations. Standard strains S.mutans and Lactobacillus were used to test the antimicrobial efficacy of modified and unmodified (control )GIC. MIC assay was done where the first three wells  were used with three different concentrations of modified GIC (1:1),(1:2),(2:1) respectively and the fourth well was kept as  control (Conventional unmodified GIC).The incubation is done under suitable conditions for varied time intervals (1h, 2h, 3h, 4h).  Compressive strength was evaluated according to ISO 9917- 1:2007 using cylindrical molds. The maximum force applied when the specimen fractures was recorded to calculate the compressive strength values in MPa.

Results: The antimicrobial activity of Cinnamon modified GIC was carried out by MIC assay where the better antimicrobial efficacy against s.mutans showed at 1:2 concentration second hourly when compared to other concentration, where in case of Lactobacillus,conventional (control) group performed better when compared with other groups and there was no significant changes in terms of compressive strength.

Conclusion: The antimicrobial activity against S.mutans was found to be better at 1:2 concentration in second hour intervals, and against Lactobacillus conventional GIC was found  better when compared to other groups. There was no change in compressive strength of cinnamon modified GIC.