Screening of phytochemical constituents and assessment of anti-cholesterol and antioxidant potentials of Coleus amboinicus
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Abstract
Background: Coleus amboinicus is also called “karpoora valli'' in Tamil. It has a lot of medicinal values, it is also used as an ornamental plant and spice. It is also commonly called Indian mint. Hypercholesterolemia is the highest risk factor and cause of cardiovascular diseases like atherosclerosis, myocardial infarction. High LDL is the cause of high cholesterol levels.
Aim-: Screening of phytochemical constituents and assessment of anti-cholesterol and antioxidant potentials of coleus amboinicus.
Materials and Methods-: Phytochemicals screening test and DPPH radical scavenging activity and anticholesterol activity were done using the ethanolic leaf extract of the plant and the results obtained were analyzed statistically by a one-way analysis of variance (ANOVA) followed by Duncan’s multiple range test was used to see the statistical significance among the groups. The results with the p<0.05 level were considered to be statistically significant.
Results: The phytochemical screening showed the rich presence of secondary metabolites in the extract. The results showed that the extracts possessed in vitro antioxidant activity in a concentration-dependent manner. The anticholesterol activity of the extract is also evident from the results. The p value is less than 0.05 and is statistically significant.
Conclusion-:It was concluded that ethanolic extract of Coleus amboinicus possessed potent anti-cholesterol and antioxidant activity.