Evaluation Of Sedative Effects of Entonox in Pediatric Patients

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V. Ranjith Akshay Seshadri, Ganesh J, Sahana Kritivasan,

Abstract

Introduction: Conscious sedation is a state of drug induced depression of the consciousness that requires no interventions to maintain patent airway. Conscious sedation is mostly administered through various routes like oral, intravenous, intramuscular and inhalational . Nitrous oxide sedation-Safest of all the forms of sedation. N2O is a colourless gas that is widely used as an inhalational anaesthetic agent that causes CNS depression with varying degree of muscle relaxation and euphoria without any effects on the respiratory system. Nitrous oxide has rapid uptake, gets absorbed quickly from the alveolus and is held in the serum as simple solution.


Aim: To explore the sedative effects of Entonox in paediatric dental patients.


Materials And Method: 48 children aged between 5-9 years old who had to undergo various procedures like extraction, pulpectomy and pulpotomy who exhibited a positive and negative behaviour rating based on the Frankl Behaviour rating scale were recruited after obtaining informed consent from the parents. Medically compromised patients, patients with previous sedation experience and with definitely negative behaviour were excluded from the study. The children were then randomly assigned into two groups Group A-Entonox 50-50, Group B- Entonox -60-40. The sedation levels were assessed using the Ramsay sedation scale and statistical analysis was done


Results: Group B had mild adverse reactions when compared to their counterpart Group A who received 50-50. The common adverse seen were nausea, vomiting, agitation, drowsiness after the reversal of the inhalation agent.  There was no statistical significance between the two groups of nitrous oxide for the sedation scores of both the group.  Patients in Group A reported that their pain experience were better which was not significantly noted in the Group B participants


Conclusion: Entonox is the safest and the most effective method of nitrous oxide sedation. Can be used for children of all age groups

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