Toxoplasma Gondii Infection Related And Interleukin 10 In Wasit Province Patients

Abstract

Materials and Methods: Two hundred and seventeen blood specimens was collected from pregnant women with previous abortion, Serological investigations were done regarding IgM and IgG in the sera of women. Those specimens were then processed by using real ELISA technique searching for evidence of Toxoplasma gondii and CMV virus, in addition to detection of Interleukin 10 in abortion women.

Result: Regarding correlation between IgM and IgG concentrations and Interleukin 10 outcomes indicated that Interleukin 10 was 287.76 pg/mL in cases of Toxoplasma IgM and 182.62 pg/mL in Toxoplasma IgG, (p value= 0.035). Effect of age on Toxoplasma IL-10 concentration in patients and control showed that the concentration of IL-10 in Toxoplasma was 248.76 pg/mL in the age group 15-24 (p value= 0.049). Effect of age on both IL-10 concentration in patients and control results showed that the concentration of IL-10 in CMV was 182.62 pg/mL in (15-24) age group, (p value= 0.021). Among collected specimens aged between 15-44 years old was included in order to test the relationship between concentration of IL-10 and age of patients, results showed that the concentration of IL-10 in both the concentration was 184.31 pg/mL in the age group 15-24 (p value= 0.010).

Conclusion: Our results showed that Toxoplasma gondii was correlated to Interleukin 10 in abortion cases.