Pharmacological Evaluation Of Gloriosa Superba Linn Flower Extract For Antiulcer Activity

Abstract

In present study the antisecretory and antiulcer potential of hydroalcoholic and petroleum ether extract of Gloriosa superba Linn flower were studied. Both extracts were tested orally at the doses of 100, 200 and 400 mg/kg using pylorus ligation, ethanol and cold stress as toxicants. Both the extracts showed significant ulcer protection at the highest dose of 400mg/kg as compared to standard. To support its antiulcer potential, the plant was investigated for free radical scavenge ring activity by lipid peroxidation. The extract showed comparative significant result. The antioxidant property may be due to presence of flavonoids and polyphenols present in extracts. From the results it was concluded that both hydroalcoholic and petroleum ether extracts of flower of Gloriosa superba is having gastric ulcero protective activity.