Eco-Friendly Syntheses And Biological Activity Of Substituted Organic Isothiocyanates Using Copper Peroxide As Desulfurizing Agent

Abstract

Isothiocyanates are heteroallenic compounds. An efficient & ecofriendly process for the synthesis of substituted organic isothiocyanates is described here. In this synthesis we used copper peroxide as desulfurizing agent. This is done by reacting substituted amines with carbon disulfide in the presence of liquid ammonia and using copper peroxide. So the reported method is a step towards the sustainable and green chemistry.   Synthesized Compounds were evaluated against Antimicrobial Activity .