Comparative Analysis Of Biochemical And Hematological Variations In Chronic Kidney Disease Patients In District Peshawar, KP, Pakistan

Abstract

Chronic kidney disease (CKD) is a worldwide public health problem. It is associated with various biochemical and hematological abnormalities that leads to morbidity and mortality. The aim of this study was to evaluate the biochemical and hematological parameters in chronic kidney disease patients in District Peshawar, KP, Pakistan. CKD has undergone significant demographic change over the past two decade as a result of globalization and climate change, the disease now poses a greater threat to human. By comparing the hematological and biochemical parameters in chronic kidney disease patients, this study seeks to better understand the ongoing endemic CKD disease in Peshawar, KP. This study was carried out as case-control study and observational research from March 2023 to September 2023. 200 patient samples that tested for chronic kidney disease was gathered and examined. According to the findings, males and female between the age of 20 and 80 are more likely to prone to kidney diseases. The elevated creatinine, urea, estimated glomerular filtration rate and ESR level was observed high in all patients.  The study also discovered an increase in biochemical parameter with marginally lower potassium levels, and lower hemoglobin level which raises the possibility of an underlying improper function of kidney.