Effect Of Candida Auris Secretions On Human-Derived Monocytes/Macrophages

Abstract

Candida auris is an emerging multidrug-resistant fungal pathogen that poses a serious threat to global public health. In this study, we investigated the effect of Candida auris secretions on human-derived monocytes/macrophages. Monocytes/macrophages play a crucial role in the innate immune response to fungal pathogens. Our results demonstrate that secretions from Candida auris can modulate the function of monocytes/macrophages, leading to impaired immune responses. This study provides important insights into the pathogenic mechanisms of Candida auris and highlights the potential therapeutic targets for the treatment of Candida auris infections.