A Review On Anti-Bacterial Activity Of Substituted Azetidinone, Benzothiazole, Thiazole, Thiadiazole, Triazole, Triazolothiazole And Naphthalene Derivatives

Abstract

This review paper discusses the potential of different nitrogen-containing ring structures, including azetidinone, benzothiazole, naphthalene, thiadiazole, and triazole, in drug development for antibacterial medications. The paper highlights the unique structural characteristics and pharmacological properties of each moiety and their potential for combating antibiotic resistance. The authors emphasize the importance of structure-activity relationship studies in understanding how modifications to these ring structures can affect their efficacy, spectrum of action, and pharmacokinetic properties. The paper also provides examples of antibacterial drugs containing these moieties and their significant antibacterial activity against various bacterial species. Overall, the paper highlights the potential of these nitrogen-containing ring structures in the development of new antibacterial drugs.