Analysis of the Phytochemical and Hypoglycemic Properties of Some Medicinal Plants of Indian Origin

Abstract

An herb with a long history of medicinal usage, Artemisia indica, is the subject of this investigation into its possible anti-diabetic benefits. Studies that looked at acute toxicity found that a hydroalcoholic extract of the terpenoids, alkaloids, and flavonoids found in Artemisia indica leaves was safe to use. Experiments on rats with streptozotocin-induced diabetes revealed that the extract has potent anti-diabetic properties. In contrast to the diabetic control group, the treatment groups showed dramatic improvements in oral glucose tolerance, higher serum insulin levels, and much lower fasting blood glucose levels. Histological analysis confirmed that the pancreatic islet structure had been preserved, and the discovery of increased insulin expression in beta cells provided further support. Furthermore, the extract reduced oxidative stress markers and demonstrated a high level of antioxidant activity. Artemisia indica may offer an alternative to current diabetic treatments due to its antioxidant and antihyperglycemic effects, according to this study's findings. Artemisia indica may have natural anti-diabetic properties; however, more study of the plant's molecular mechanisms and therapeutic uses is required.