Hair Growth Promoting Effect Of Topical Poly Herbal Oil On Sprague Dawley Rats

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Farah Gul
Farina Kanwal
Nur Ul Ain
Yaqoob Ur Rehman
Ziaf Ur Rahman
Shuja Ud Din Badar
Salimullah Khan
Ismail Shah
Maqsood Ur Rehman
Ajab Khan
Guloona Sajjad

Abstract

Hair loss is a common concern for both men and women, usually characterized by hair thinning, dandruff and extreme hair fall or shedding. Although synthetic remedies for hair loss are available but they often have appalling side effects and do not offer a permanent and long-lasting solution. The goal of the study was to formulate a herbal hair repair oil that would promote hair growth and repair while reducing hair loss. It was also aimed to examine and compare the effects of various herbal oils on hair growth in Sprague Dawley rats. For this purpose, a variety of herbs were selected including, the leaves of Hibiscus rosa sinensis, Murraya koenigii, Melaleuca alternifolia, Monarda fistulosa and Salvia rosmarinus. Castor oil, coconut oil, olive oil, almond oil, sesame oil, peppermint essential oil, and rosemary essential oil were among the other oils used in this investigation. The formulated repair hair oil was evaluated through physical, chemical, and hair growth tests by applying it topically to shaved albino rats. Primary skin irritation, antioxidant activity and hair length tests were performed. The results of the hair growth study were compared with locally purchased hair oils. Poly herbal hair repair oil demonstrated the best results among the tested samples in terms of increased hair length, efficacy, safety, promising physicochemical properties, antioxidant activity and hair growth promotion in animal models.  

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Author Biographies

Farah Gul

Medicinal Botanic Centre, Pakistan Council of Scientific and Industrial Research (PCSIR), Laboratories Complex, Peshawar, Khyber Pakhtunkhwa, Pakistan.

Farina Kanwal

Medicinal Botanic Centre, Pakistan Council of Scientific and Industrial Research (PCSIR), Laboratories Complex, Peshawar, Khyber Pakhtunkhwa, Pakistan

Nur Ul Ain

Department of Pharmacy, Abasyn University, Peshawar, Khyber Pakhtunkhwa, Pakistan

Yaqoob Ur Rehman

Medicinal Botanic Centre, Pakistan Council of Scientific and Industrial Research (PCSIR), Laboratories Complex, Peshawar, Khyber Pakhtunkhwa, Pakistan

Ziaf Ur Rahman

Medicinal Botanic Centre, Pakistan Council of Scientific and Industrial Research (PCSIR), Laboratories Complex, Peshawar, Khyber Pakhtunkhwa, Pakistan

Shuja Ud Din Badar

Medicinal Botanic Centre, Pakistan Council of Scientific and Industrial Research (PCSIR), Laboratories Complex, Peshawar, Khyber Pakhtunkhwa, Pakistan

Salimullah Khan

Department of Pharmacy Garden Campus, Abdul Wali Khan University Mardan, Khyber Pakhtunkhwa, Pakistan.

Ismail Shah

Department of Pharmacy Garden Campus, Abdul Wali Khan University Mardan, Khyber Pakhtunkhwa, Pakistan.

Maqsood Ur Rehman

Department of Pharmacy, University of Malakand, Chakdara Dir Lower, Khyber Pakhtunkhwa, Pakistan

Ajab Khan

Rehman College of Dentistry, Peshawar, Khyber Pakhtunkhwa, Pakistan

Guloona Sajjad

Pakistan International Medical College, Peshawar, Khyber Pakhtunkhwa, Pakistan