Correlation Of Lipid Metabolism Genes With Drug Resistance Markers

Abstract

One defining feature of cancer cells is metabolic pathway dysregulation, which prevents them from meeting their bioenergetic and biosynthetic demands.  Lipid moieties are physiologically and clinically significant because they are a concentrated source of energy and a source of numerous precursors that fuel cancer's high growth rate Therefore, this review set out to compile and organize data about how samples are prepared for lipid analysis in relation to obesity research.  The emergence of medication resistance is a major challenge in cancer treatment.  In both the local and TCGA cohorts, research examining the relationship between drug resistance genes and lipid metabolism genes found that ABCC1 was positively associated with CERK and SPHK1.