Mycosynthesis of AgNPs from Candida albicans and its antagonistic activity against pathological factors the urinary and reproductive system in women

Abstract

This study was conducted in the Department of Life Sciences of the College of Education for Pure Sciences/ University of Thi Qar, Iraq. During (February - September 2022). To study the inhibitory effect of silver nanoparticles manufactured from yeast (Candida albicans) on the fungal and bacterial pathogens that infect the system urinary and genital in women.  Four species of yeast belonging to the genus Candida (C. albicana, C.glabrata, C.tropicalis and C. krusei) and five species of bacteria (Escherichia coli, Proteus spp, Klebsiella spp, Staphylococcus aureus and Streptococcus spp) were tested. Five variants of a solution of silver nanoparticles synthesized from Candida albicans were used in the study (0 control, 25%, 50%, 75%, and 100) concentration. Results confirmed that there are significant differences between Candida spp. and concentrations used for silver nanoparticles in the experiment. C. krusei  were recorded the highest value for the diameter of growth inhibition 24.26 mm, and 100% concentration were recorded the highest inhibition rate  23.98 mm while 25%  concentration were recorded  lowest inhibition value  13.70 mm. Also, results confirmed that there are significant differences between species and genuses of bacteria and concentrations used for silver nanoparticles in the experiment. Staphylococcus aureus were recorded highest value of growth inhibition diameter 12.18mm, and 100% concentration were recorded the highest inhibition rate 15.82 mm.