Identification Of Mirror Repeats Within The Trp53 (P53) Gene Of Mus Musculus

Abstract

Various types of repetitive elements have been identified within the genome of organism such as direct repeat, indirect repeat and tandem repeat. One such repeats which is not widely examined in Mus musculus is mirror repeats. The present investigation aims to determine the mirror repeats in Trp53 gene of Mus musculus. Trp53 gene plays a significant role in cell cycle arrest, maintenance of stem cell through development, apoptosis, DNA repair and cellular senescence. By using a simple approach we have identified mirror repeats within the Trp53 gene. As a result 281 mirror repeats were recognized within the complete gene and 27 mirror repeats in the eleven exons of Trp53 gene of Mus musculus. We concluded that these mirror repeats is well distributed in within genome of Mus musclus and other organism genome.