Synthesis and Biological Evaluation of Some Ethers Acetylene Compounds Derivatives of Oxazole

Abstract

In this present synthesis anew series of some ethers acetylene compounds derivatives of 

2-p-hydroxy benzyl-4,5-ditolune oxazole.

2-p-hydroxy benzyl-4-tolune-5-phenyl oxazole.

2-p-hydroxy benzyl-4,5-di-p-chloro phenyl oxazole.

2-p-hydroxy benzyl-4,5-di-p-bromo phenyl oxazole.

2-p-hydroxy benzyl-4-p-dimethyl amino phenyl -5-phenyl oxazole.

Treated with 3-bromo propyne yielded series of new ethers acetylene oxazole compounds were characterized by ( FT-IR , 1HNMR , 13CNMR , C.H.N ) in this study of the effect compound in the two types of bacteria isolated from amedical condition ( human ) .