Evaluation Of Anti-Inflammatory Property of Mouthwash Using Ethanolic Extract of Clitoria Ternatea- An In Vitro Study

Abstract

BACKGROUND: Clitoria ternatea, commonly known as butterfly pea, is a plant species belonging to the family Fabaceae.C. ternatea ethanolic extract (CTEE) is effective against oral pathogen, Streptococcus mutans. Clitoria ternatea is a well-known bioactive plant used to treat several inflammatory ailments in Ayurvedic system of medicine in India. Inflammation is caused by release of chemicals from tissues and migrating cells. Anti-inflammatory agents block certain substances in the body that cause inflammation.

 AIM:  To evaluate the anti-inflammatory activity of mouthwash using ethanolic extract of Clitoria ternatea.

 MATERIALS AND METHODS: The research involved preparing mouthwash using ethanolic extract of Clitoria ternatea. These were tested for anti-inflammatory activity by BSA assay and EA assay.

RESULTS: The study shows that the anti-inflammatory activity of mouthwash increased as the concentration increased in a dose dependent manner when compared with the control, 50 µl showed the highest % of inhibition 80% in both BSA and EA Assay. Hence can act as a good anti-inflammatory control.

CONCLUSION: Mouthwash using ethanolic extract of Clitoria ternatea were proved to possess strong level of anti-inflammatory activity. Also, the results of the study reinforce the opinion that medicinal properties of the plant  are promising sources of potential anti-inflammatory agents which may be useful for various dental therapeutic procedures.