Estimation the concentrations of Immunoglobulin (IgM and IgG), C3, C4, and Total protein in serum of Covid -19 Vaccinated person

Abstract

Immunoglobulin and complement proteins play a key role in immune system health and function, orchestrating a range of innate and acquired responses against pathogens such as viruses. It may work to enhance the process by which antibodies neutralize viruses, as well as to promote immune cell phagocytosis of viruses and result in virus lysis. Vaccination has created a great step toward improving global health. The innovation and application of vaccinations have contributed significantly to the control of infectious illnesses. A study was conducted randomized on vaccinated people in Iraq/Babylon governorate for both sexes. The number of vaccinated people was 695 people, including 561 people taking the Pfizer vaccine, 120 people taking Sinovac, and 14 people taking AstraZeneca. The results appeared to investigate the levels of IgG, IgM, C3, C4, and total protein concentrations in the serum of the vaccinated people and compare them with unvaccinated people. The study found elevated levels of C3 in the vaccinated people with AstraZeneca 328.900029.01293  than in control 282.02846.187, while C4 concentrations were lower in the vaccinated group (77.550021.40537, 74.966715.95755, 73500027.36110) than control 89.006014.18771. The total protein, IgG, and IgM concentrations were higher in the vaccinated people than in the control group.